The Gunners have been the division's draw specialists this campaign having been held 13 times and it looked to be going the same เกมยิงปลา way after a goalless first half.
But the hosts sprung into action immediately after the restart with Eddie Nketiah's no-look strike from Nicolas Pepe's cutback clipping the top of the crossbar.
Mikel Arteta's side broke the deadlock on 54 minutes through Pierre-Emerick Aubameyang's well-placed header and Pepe doubled the lead just three minutes later with a neat, first-time finish.
Mesut Ozil poked in a third late on from substitute Alexandre Lacazette's pass and the Frenchman converted a fourth in injury-time.
Newcastle attempted to play further forward คลิปหลุด after conceding but were restricted to few opportunities - the dangerous Allan Saint-Maximin coming closest with a curling strike that rattled the post.
Arsenal's win moves them up into the top half of the table in 10th place - six points behind north London rivals Tottenham, who claimed a last-gasp winner over Aston Villa to go fifth.